Home Improvement & Renovation Aklief (trifarotene): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD 1 month ago 0 Aklief (trifarotene) is a fourth-generation topical retinoid designed to treat acne on both the face and body.... Read More Read more about Aklief (trifarotene): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD